Tag:biotechnology
Dire Wolves Highlight Dire Need for De-extinction Regulation
On April 7, 2025, Colossal Biosciences announced that it had successfully created dire wolves, a species that had been extinct for over 10,000 years, in what is considered a breakthrough in the science of de-extinction. Although it sounds like a work of science fiction, Colossal used dire wolf DNA found in a 13,000-year-old tooth and a 72,000-year-old ear bone to make 20 edits to the DNA of modern gray wolves leading to the birth of 3 dire wolf puppies in the fall and winter of 2024. While the science community both celebrates the breakthroughs in genetic engineering, considers the benefits that this technology can have on modern endangered species, and debates the validity of calling genetically modified gray wolves true dire wolves, it is clear that the regulatory framework of the United States is not yet sufficiently prepared to examine the legal and ethical considerations that come with de-extinction technologies. Though dire wolves were the breakthrough, they are not the end goal for Colossal as it now turns its focus to other popular extinct species such as the wooly mammoth, dodo bird, and Tasmanian tiger. To adequately keep up with these changes in genetic and environmental science, the United States must act quickly to develop an agile multi-agency regulatory framework that can guide the country and world as a whole safely into the new age of de-extinction.
Joint Agency Decision Serves Up A New Regulatory Framework For Cell-Based Meat
Following a public meeting in October, the Food and Drug Administration (FDA) and the United States Department of Agriculture (USDA) agreed to share joint regulation of cell-culture “meat” technology. This decision came on the tail end of public squabble between the two regulatory bodies regarding the oversight of cell-culture, or lab-produced meat. The regulatory framework for this type of quasi-agriculture has been unclear, especially after the White House Office of Science and Technology Policy issued the Coordinated Framework for the Regulation of Biotechnology initiative that attempted to coordinate the roles of various agencies involved in emerging biotechnology. The new, definitive regulatory structure has been thoroughly praised and welcomed by top cell-culture meat companies, who have expressed open frustration with the older, confusing framework, claiming that it hindered both consumer protection and technological innovation.